Commander Bristle was first seen in the space station at the stage making a speech to the audiences that the long-awaited mission to Mars is ready to be launched and brings Biff Buzzard and Buzz Blister who are both selected for the mission. As Buzz is making a speech, the stage curtain behind them collapses and he, Bristle and Biff check it and Tom and Jerry emerge from the under of the curtain covered in green paint. One of the audiences mistook them for Little green men and they flee and Buzz and Biff hide behind Dr. Gluckman who was delighted to see aliens. Bristle then greets them, but the green paint clears away from them, causing him to realizes they are not aliens, Buzz then realizes it's only a cat and Biff looks at Jerry who waves at him and it's a mouse. Bristle yells Biff, Buzz and Dr. Gluckman to get them, but they escaped unharmed and end up beating each other then chases them, Tom is caught and thrown out while Jerry escapes. During the food dehydration testing, Dr. Gluckman shows him how a dehydrated pizza dinner powder rehydrates by pouring water and the dehydrated pizza dinner powder changes into a pizza dinner. Commander Bristle tastes one slice and it's delicious just like his mother trying to make for him. He returns to his office as soon he orders the workers to bring the dehydrated meals into the rocket. Jerry then climbs into the table and opens the dehydrated turkey dinner and rehydrated it, and accidentally spilled the small water vial on the dehydrated cheeseburger rehydrating it sending it across the room and one of them hits a water container and it fell into the floor spilling it hitting a half pile of boxes of dehydrated meals nearby rehydrated them in the process and floods the nearby hallway, engulfs the workers and jamming Commander Bristle's office door. Commander Bristle hears this commotion and checks it and tries to pushes his office door open and fell face flat on the spilled rehydrated meals and he asked the workers what is going on and one of them tells him that the dehydrated meals have exploded and they don't know why it happened. Commander Bristle knows they are being rehydrated. Another worker tells them that the dinner got wet, which Commander Bristle that's what rehydrated means and the worker that the meal goes Kablooey. Commander Bristle explains to him that things won't get kablooey on their own and there must be a reason for the kablooey and demands the workers to find that reason or they will go kablooey which they agree. Jerry then emerges from the pile of meals, one of the workers then realizes it was Jerry who was responsible for the dehydrated meals go kablooey and they and Commander Bristle chase him and end up crashing into each other. Dr. Gluckman then tells Commander Bristle that they have a mouse which he already knew. Dr. Gluckman knows how to get rid of Jerry and Tom whom they threw out was the one who could help them get rid of Jerry. Commander Bristle orders the workers that they need to find Tom and bring him back and Dr. Gluckman shows a rehydrated fish to them which could help bring Tom back. The workers soon find Tom and lures him in with a rehydrated fish. Commander Bristle orders Tom to get rid of Jerry, which he did so. When Biff and Buzz are in the rocket, he contacts them in their monitor and asks them if everything is set up as they will begin the countdown to launch the rocket and they reply that everything is set up. After the rocket has launched, he then congratulates them that they leaving Earth's atmosphere and zero gravity is should start by now. Unknown to him Tom and Jerry are stowed on the rocket and Dr. Gluckman informs him that the rocket's condition will crash into the sun and he contacts Biff and Buzz to go outside the rocket and open the fusebox and trigger the wire of the antenna, which they did and accidentally triggers the lightspeed of the rocket by Jerry which lead them both to fight each other after Buzz was able to stop it. Commander Bristle informs them that they are in Mars and orders to get to the lander, they refuse, but reluctantly do so after he threatens them to be left out there. Biff and Buzz return to Earth after the mission and they celebrate but this is short-lived when aliens arrive. Dr. Gluckman and Bristle start to fight each other as one of the aliens are announcing that they will conquer Earth. However they are saved when Tom and Jerry arrive with a redeemed Peep forcing them to retreat and integrate Biff and the others, and the aliens sent a robot to deal with them. But the robot is destroyed with help from Spike the Bulldog. Dr. Gluckman, Bristle, BIff and Buzz thank Tom, Jerry, and Peep for their actions.