Jerry and Jumbo is the 74th entry of the classic series. This entry was created in 1951, directed by William Hanna and Joseph Barbera and produced by Fred Quimby with music by Scott Bradley. It was animated by Kenneth Muse, Irven Spence and Ed Barge with backgrounds by Robert Gentle and was released to theaters on February 21, 1953 by Metro-Goldwyn-Mayer.
A baby elephant named Jumbo and his mother are on a passing train, until Jumbo falls off and he rolls into Tom & Jerry's house and lands on Tom's basket. Jumbo hides under Tom's blanket as Tom goes to sleep. As Tom unawarely pushes him to get comfortable, Jumbo pulls his trunk back in time. Jumbo then steps out of the basket and runs around with Tom on top of him, causing Tom to bump his head on a cabinet. Tom, confused, goes back to sleep.
Jumbo then sucks up all of Tom's milk from 15 feet away, waking the cat up again. As Tom storms into the kitchen after Jerry, Jumbo hides. When Jerry is drinking milk from the refrigerator, a drop of milk falls from his whisker, leading Tom to blame Jerry. As Tom moves to smash Jerry with the milk bowl, Jumbo sucks Jerry away just in time.
Tom, puzzled, walks away as Jerry and Jumbo befriend each other. Wanting to please his new friend, Jerry retrieves a bag of peanuts by standing on Jumbo, but accidentally breaks it over Jumbo's head, waking Tom up for a third time. Jumbo flees, summoning Jerry with his suction, into a closet. As Tom examines the peanuts, Jumbo sucks the peanuts under the door, such that they appear marching toward the door to Yankee Doodle. This frightens the cat and leads him toward the door. As Tom tries to force entry, Jerry shares his plans to Jumbo and paints Jumbo brown with a black nose to turn him into a giant lookalike of Jerry.
They then unlock the door; as Tom opens it, both Jerry and Jumbo whack him with a hammer. Tom, puzzled, peeks inside, but instantly shuts the door when he sees Jumbo. Tom grabs a baseball bat, looking to beat up Jumbo, but instead gets whacked by Jerry again. Losing his temper, Tom pulls the door open and charges in, bat at the ready, only to run into Jumbo, who faces him down and punches Tom with his trunk, hurling the cat across the room and into a desk. Tom then returns to the door and opens it for a fifth time, taking shelter behind it, but finds that nothing happens. Tom then hears a crashing noise and chases Jerry. As Tom runs back and forth, he sees Jumbo on the other side. Tom runs across a second time and sees Jerry, much to his relief, but after running across four times, he sees both Jerry and Jumbo.
Tom then pokes his head over the wall. He sees Jumbo, then Jerry, then Jumbo, then Jerry. When he sees a huge mouse hole next to Jerry's, Tom finally understands the situation and yelps in fear before putting a large mousetrap near Jumbo's hole and fleeing. Jumbo is quick on the ball, however, turns the trap around and begins the suction. Tom peers back and gasps as he gets closer toward the trap, but before he can move or even grab onto something that can help him to escape the suction, he ends up being sucked in and gets caught in the trap, which snaps shut on his behind. Tom lets out a super loud scream of pain, and looks at his tail, which is a form of a large bump. Tom chases after Jerry, who runs into a small mouse hole. Tom gropes for Jerry's tail, but grabs Jumbo's instead, causing Tom to fall back carrying Jumbo and Jumbo to flatten Tom onto the stairs.
Tom, now deciding to meet force head-on, grabs a shotgun and chases Jerry, while Jumbo hides. Jumbo's mother then pokes her head through the window and hugs him before scooping him up as Tom continues to shoot at Jerry. Jerry runs outside as Jumbo calls to him from the garage with a paintbrush, with Tom following. Jerry jumps out, followed by Jumbo and his mother, decked out in mouse colors too. The sight of this utterly terrifying display finally seems to break the poor cat completely. Tom leaps a foot back, and as his gun droops down like limp spaghetti, he lets out a nervous chuckle. Turning to face the camera, Tom grins insanely while mimicking the sizes of the "mice" before he runs off in fear and cackling maniacally (having that Tom has gone insane) while breaking through a wall and a fence.
- This cartoon doesn't have the Western folk belief of elephants being afraid of mice. In fact, Jumbo was more afraid of Tom than Jerry. Jumbo becomes Jerry's friend and ally in this cartoon and even pretends to be a giant-sized mouse to scare Tom. Jumbo even has his own mother painted to look like an even bigger giant mouse, enough to put Tom into a nervous breakdown.
- When Tom drops the gun to scream like crazy in the end, Tom can be seen "teleporting" to the place that the gun fell for 1 second.
- When the circus train went into the tunnel when it blew its whistle a second time the whistle came from Great Western #51 and it was slightly slowed down and the pitch was slightly low and the Great Western #51 is currently on static display.