Slicked-up Pup is a 1951 American one-reel animated cartoon and is the 60th Tom and Jerry cartoon directed by William Hanna and Joseph Barbera and produced by Fred Quimby. The cartoon was scored by Scott Bradley and animated by Ed Barge, Kenneth Muse, Irven Spence and Ray Patterson. It features the second appearance of both Spike and Tyke together.
Spike has just bathed Tyke so that he is nice and clean. However, Spike is horrified when, through the constant chases of Jerry and Tom, Tyke ends up getting dirty by falling into a muddy puddle. Spike grabs Tom and scolds him. Tom quickly rushes off with the muddy pup and returns almost instantly with Tyke cleaned up. Spike then warns Tom that if Tyke isn't clean when he comes back, he'll tear him limb from limb, Tom nods his head in fright. The screen pans over to Jerry, who nods as well with a grin on his face, obviously planning to make this difficult for Tom. Before Spike leaves, he growls at Tom with fear.
As Tom sits down on the same wooden platform that Tyke is lying on, one of the wooden planks catapults Tyke into the air, and Tom narrowly saves Tyke from falling into the same muddy puddle. Tom overhears Jerry's laughter and chases after him. Jerry quickly stops the cat, and challenges him to a game of tic-tac-toe on Tyke's back. Tom wins and resumes chasing Jerry, before suddenly realizing what he's done, and promptly returns to Tyke to rub off his pencil marks. Jerry hurls a tomato at Tom, but Tom quickly ducks so that it avoids him. Realizing that it will hit Tyke instead he yelps with fear and Tom rushes back and stands directly in front of the pup so that the tomato does hit him, after all. Then he wipes the tomato off.
The chase resumes until Tyke ends up with a jar of ink spilled on him. Tom panics after seeing Tyke covered in ink and attempts to rub the ink off but fails. Tom grabs some paint tins, painting Tyke first white, then gray, but Jerry pushes the paint containers so that Tom ends up dipping his paintbrush into a variety of different colors. Tyke has now been painted a multi-colored mess of reds, blues, greens and yellows. Horrified, Tom grabs a hose so that he can wash the paint off, but Jerry connects the other end of the hosepipe to a large container of tar. Out of the hosepipe comes thick, black, sticky tar. Tom sees that Spike is approaching, and decides he must act quickly. Tom spots a pillow hanging on a washing line, and stuffs Tyke into it and takes him out, leaving Tyke covered in feathers. He then places a red glove on Tyke's head and a clothes peg on his mouth, so that Tyke crudely resembles a chicken of sorts. Spike is surprisingly fooled and walks off. However, Tyke removes the peg from his mouth and bites Tom's tail. Tom screams in pain and alerts Spike, causing him to turn and attack.
Tom rushes off and hides in the laundry room, putting Tyke inside a washing machine. Just as Tom is adding soap flakes, he is stopped by Spike, who takes Tyke out of the washing machine. Spike realizes what Tom has done to Tyke pours the box of soap flakes over Tom's head as he knew about what happened just now to Tyke angrily and shoves a soap bar in his mouth, before shoving him into the washing machine and slamming the washing machine door on him. The cartoon concludes with poor Tom spun and washed around the washing machine, being watched by Spike and Tyke joined by Jerry who was actually the culprit responsible for making Spike's son look the way he did. We spot naughty little Jerry giving Tom a wave in a mocking manner.
- This one of the Tom and Jerry cartoons where Jerry successfully frames Tom.
- The short was theatrical re-released in theaters with The Adventures of Elmo in Grouchland in 1999.